ORGAN-SPECIFIC ALTERATIONS IN FATTY ACID DE NOVO SYNTHESIS AND DESATURATION IN A RAT MODEL OF PROGRAMMED OBESITY

Organ-Specific Alterations in Fatty Acid De Novo Synthesis and Desaturation in a Rat Model of Programmed Obesity

Abstract Background Small for gestational age (SGA) leads to increased risk of adult obesity and metabolic syndrome.Offspring exposed to 50% maternal food restriction in utero are born smaller than Controls (FR), catch-up in growth by the end of the nursing period, and become obese adults.The objective of the study was to determine stearoyl-CoA des

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De Novo Transcriptome Analysis Provides Insights into Immune Related Genes and the RIG-I-Like Receptor Signaling Pathway in the Freshwater Planarian (Dugesia japonica).

BACKGROUND:The freshwater planarian Dugesia japonica (D.japonica) possesses extraordinary ability to regenerate lost organs or body parts.Interestingly, in the process of regeneration, there is little wound infection, suggesting that D.japonica has a formidable innate immune system.The importance of immune system prompted us to search for immune-re

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Identifying inversions with breakpoints in the Dystrophin gene through long-read sequencing: report of two cases

Abstract Background Duchenne Muscular Dystrophy Microphone (DMD) is an X-linked disorder caused by mutations in the DMD gene, with large deletions being the most common type of mutation.Inversions involving the DMD gene are a less frequent cause of the disorder, largely because they often evade detection by standard diagnostic methods such as multi

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